Corra, GM., de C. Alcntara, AF. He has B.Sc.,and M.Sc. Contamination of medicinal plant could be as a result of contaminants (such as heavy metals, aflatoxin and pathogenic microbes) from soil and manner of herbal preparations [4]. Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. To create additional collections, you must be a paid member of our site. Check these Great Plant Combination Ideas with Justicia, Eye-Catching Retaining Walls and Staircases, An Eye-Catching Mediterranean Garden with Agave, Aloe and Pincushion, A Striking Water-Wise Border with Agave, Cactus and Ocotillo, A Beautiful Duo with Agave 'Blue Flame' and 'Blue Glow', A Long-Lasting Summer Garden Idea with Marigold and Sage, 8, 9, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, H1, H2. Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. The research work was carried out in collaboration between all authors. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. California Privacy Statement, Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. Rich on haematological and biochemical parameters in healthy Wistar rats. Cardioprotective role of Justicia traquebareinsis Linn. Haematological and biochemical studies on Justicia carnea - PubMed This is . Liver and kidney in all treated groups maintained similar activities of catalase (CAT) compared to the control. The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. and M.Sc. The authors acknowledge the Director and staff of Peak Health Diagnostic and Research Laboratory, Ibadan, Oyo State, Nigeria, for the technical support and interpretation of the histology. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. long (20 cm), densely packed with pink to crimson tubular flowers. Only plants will be removed from the collection. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. Another strong benefits of justicia carnea leaves is in lipid profile. Cookies policy. Antioxidants & redox signaling Forum Review. 2023 BioMed Central Ltd unless otherwise stated. 217-230. The very tropical looking Brazilian plume with its bright inflorescence is definitely a unique addition to gardens. J Ethnopharmacol. 2003;66:1499503. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. Sci. You can add milk or honey for taste before drinking. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. Recently, it has also been reported that the species possess cardioprotective properties, antioxidant and are generally rich in vitamins and minerals [10,11,12]. Anal Biochem. How often should it be watered? Ewe eje or ewe ajeri is prepared differently by different folks. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. These animals were obtained from the animal house of the Department of Chemical Sciences, Ladoke Akintola University of Technology Ogbomoso Oyo State, Nigeria. 2002;82:197205. 1.3.1 Aetiologyof Anaemia Anaemia may be due to a single factor such as a nutritional deficiency or multifactorial (McEvoy, 2013). Justicia carnea and Cnidoscolus aconitifolius were tested for their capacity to ameliorate the fecundity of chloramphenicol-induced lymphoma in rats. Acute and chronic toxicity of the aqueous extract of Artemisia afra in rodents. J Ethnopharmacol. volume7, Articlenumber:2 (2021) de Smet, P. A. 200, 500 and 1000 mg/kg bw of Justicia carnea showed a significant (p<0.05) decrease in the activities of ALT, AST and ALP, and bilirubin level while total protein and albumin levels increased significantly (p<0.05) when compared with the rats treated with CCl alone. Occupational Health and Safety in the Care and Use of Research Animals. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. The description of these plants has been written based on numerous outside resources. Information from this source is evidence-based and objective, and without commercial influence. Rats that received 50 and 100mg/kg body weight JCEE showed significant (p<0.05) increase in liver weight while other doses showed no significant difference compared to the control. This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. Studies on The Phytochemical and Nutritional 3rd ed. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. Cut from the stem, some fresh or dried Justicia carnea leaves. Each of the rats received 1500, 2900 and 5000mg/kg body weight of JCEE respectively and examined within 24h for manifestation of toxicity. Justicia Carnea is a flowering plant that may be found in our neighborhood. Justicia carnea belongs to the family- Acanthaceae. Biomed Environ Mass Spectrom 1988;15(8):413-417. Relative to the control, liver of rats treated with doses of J. carnea ethanol extract showed varied degree of hepatic injury in a dose dependent manner. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. There are several nutritional benefits of justicia carnea leaves. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Effects of ethanol leaf extract of Justicia carnea on serum SOD 1978;90:819. 2015;6(7):265270. Infertility after therapy, in particular, imposes a significant mental strain on young patients. Ewe eje is safe and healthy for consumption. Justicia carnea is commonly cultivated and grown as an ornamental potted plant. The aim of this study is to evaluate the effects of J. carnea leaf extract on hematology indices and organ antioxidant system in healthy wistar rats. We'll respect your privacy and unsubscribe at any time. Tietz NW. Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves By entering your email address you agree to receive a daily email newsletter from Plant Care Today. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. 2012; 22(1):220238; https://doi.org/10.1590/S0102-695X2011005000196. Also observed is a distortion in the walls of the blood vessels (red arrow), pyknotic hepatocytes and signs of inflammation (red arrow), Photomicrographs of kidney sections stained with Haematoxylin and Eosin (Mag. Therapeutic Research Faculty 2020. The result of hematology indices is presented in Table3. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko Haematoxic effects following ingestion of Nigerian crude oil and crude oil polluted shellfish by rats. Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Biomed Res. Ogwu obara can act as a blood tonic for women during menstruation. 2003;84:99104. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. Nutritional Composition of Ewe eje (Justicia carnea leaf). Studies on the Phytochemical and Nutritional Composition of Aqueous Leaf Extract of Justicia Carnea and its Effect on Some Biochemical Parameters in Anaemic Rats. However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. PubMedGoogle Scholar. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. Phytochemical profile, antioxidant, -amylase inhibition, binding Another plant with this benefit is fertility tree. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. Leaf extract in isoproterenol induced myocardial infarction in albino rats. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Justicia carnea has been used in traditional medicine to treat diabetes. ESA conceived and designed the study. B-vitamins are good sources of energy. Ewe eje is a rich source of phytochemicals, minerals and vitamins. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. Vitamin C and E are antioxidants. Where, A=absorbance, TV=total volume, SV=sample volume, =extinction coefficient, TP=total protein. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. It also increases good cholesterol levels. Sinha AK. Meth Enzymol. Buege JA, Aust SD. Not sure which Justicia to pick?Compare All Justicia. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. There may be some problems if the air is too dry in winter. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. The plant is transplanted in the spring. The absorbance of the supernatant was measured against reagent blank at 532nm. While the renal tubules across the tested groups were normal with the interstitial spaces showing moderate congestion and hemorrhage, there appeared some abnormalities in the renal cortex (such as few sclerotic glomeruli with moderately dilated capsular spaces) resulting in fair architectural structure of the kidney (Fig. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). Inter J Pharm Sci Res. CAS These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. Elevated activity of catalase in liver and kidney across tested doses of J. carnea ethanol extract showed no significant effect compared to the control. Rats were routinely observed for signs of toxicity. Names of Justicia Betonica in various languages of the world are also given. It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013).
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